Preparation of desymmetrised meso-tartrate derivatives—synthesis and utility of (R′,R′,R,S)-2,3-butane diacetal protected dimethyl tartrate
Abstract
The synthesis of 2,3-butane diacetal protected dimethyl tartrate (R′,R′,R,S)-1 using a chiral memory protocol and its utility for the preparation of desymmetrised meso-tartrate derivatives through selective transesterification and aminolysis of the spatially different carboxylate termini is described.