The 1,4-addition reaction of lithium derivatives of N,N-disubstituted phenylacetamides with 2-arylmethylene-1,4-butanolides gives the corresponding N,N-disubstituted 2-(1-aryl-2-carbamoyl-2-phenylethyl)-1,4-butanolides 3a–f as diastereoisomeric mixtures with 40–68% yields.
T. P. Cholakova, A. A. Dobrev, A. B. Kanchev and P. P. Mikhailova, J. Chem. Res. (S), 1999, 546 DOI: 10.1039/A904005F
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