Synthesis of a Heteroannulated Furanose via Intramolecular Michael Addition in an ω-Hydroxy α,β-Unsaturated Nitrile
Abstract
An highly stereospecific Michael addition in the ω-hydroxy α,β-unsaturated nitrile 4, obtained from ‘diacetone glucose’ 2, leading to annulated furanose 7 is reported.