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Issue 7, 1999
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Efficient One Step Transformation of Carboxylic Acids to Nitriles with the Carbon Chain Shortened by One Carbon Atom

Abstract

Nitrozation of ω-substituted alkanoic acids of the general formula X(CH2)nCO2H (X=Cl, CO2H, CO2Me, PhthN), bulky substituted alkanoic acids, arylacetic acids containing electron withdrawing substituents in the aromatic ring, o-tosylhydroxyphenylacetic acids and N-phtaloilaminophenylacetic acids yield nitriles with the carbon chain shortened by one (or two for dicarboxylic acids) carbon atom.

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Article type: Paper
DOI: 10.1039/A900239A
Citation: J. Chem. Res. (S), 1999,0, 407-407
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    Efficient One Step Transformation of Carboxylic Acids to Nitriles with the Carbon Chain Shortened by One Carbon Atom

    Y. I. Smushkevich, V. Y. Smushkevich and M. I. Usorov, J. Chem. Res. (S), 1999, 0, 407
    DOI: 10.1039/A900239A

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