The first efficient bovine serum albumin catalyzed asymmetric oxidation of tertiary amines to the corresponding N-oxides via kinetic dynamic resolution
Abstract
Unsymmetrical teriary amines were oxidized with a few oxidants in the presence of bovine serum albumin to give the corresponding N-oxides of the highest optical purity ever reported (up to 66%) for the reaction of asymmetric oxidation of amines via their kinetic dynamic resolution.