Issue 9, 1999

A new germanium based linker for solid phase synthesis of aromatic compounds

Abstract

An efficient three-step synthesis of germyl linker precursor 4 is described which enables a simple two step immobilisation of lithiated aromatics to Argogel™ polymer; cleavage from the polymer support via ipso-degermylation with TFA, ICl, Br2 and NCS provides protio-, iodo-, bromo- and chloro- aryls, respectively.

Additions and corrections

Article information

Article type
Paper

Chem. Commun., 1999, 835-836

A new germanium based linker for solid phase synthesis of aromatic compounds

A. C. Spivey, C. M. Diaper and A. J. Rudge, Chem. Commun., 1999, 835 DOI: 10.1039/A900915I

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