Conversion of a new chiral reagent Δ-[Ru(bpy)2 (dmso)Cl]PF6 to Δ-[Ru(bpy)2(dmbpy)]PF6Cl with 96.8% retention of chirality (dmbpy = 4,4′-dimethyl-2,2′-bipyridine)

Abstract

The new chiral ruthenium bis(bpy) sulfoxide reagent, Δ-cis-[Ru(bpy)₂(dmso)Cl]PF₆ (100% ee following HPLC resolution) is used to prepare Δ-[Ru(bpy)₂(dmbpy)][PF₆]Cl in excellent yield (97%) with almost complete retention of absolute configuration (96.8%), as confirmed by X-ray crystallographic studies on a single enantiomer of [Ru- (bpy)₂(dmbpy)][PF₆]Cl (obtained without resolution or chromatographic methods) and by analysis of the optical properties of both the precursor and product.