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Issue 7, 1999
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Catalytic asymmetric carbon–carbon bond forming reactions: preparation of optically enriched 2-aryl propionic acids by a catalytic asymmetric hydroboration–homologation sequence†

Abstract

A new catalytic asymmetric one-carbon homologation strategy has been developed which employs a rhodium catalyzed asymmetric hydroboration followed by homologation with LiCHCl2 and oxidation to generate 2-arylpropionic acids of high enantiomeric purity.

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Article information


Chem. Commun., 1999, 611-612
Article type
Paper

Catalytic asymmetric carbon–carbon bond forming reactions: preparation of optically enriched 2-aryl propionic acids by a catalytic asymmetric hydroboration–homologation sequence†

A. C. Chen, L. Ren and C. M. Crudden, Chem. Commun., 1999, 611
DOI: 10.1039/A809435G

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