Bidirectional asymmetric allylboration and the synthesis of C2 symmetric 3-methylenepentane-1,5-diols
Abstract
The double allylboration of aldehydes using 1,3-bis(diisopinocampheylboryl)-2-methylenepropane under Brown’s salt-free conditions provides C2 symmetric 3-methylenepentane-1,5-diols in excellent enantiomeric excess.