Issue 22, 1999

Directed ortho-metalation and Suzuki–Miyaura cross-coupling connections: regiospecific synthesis of all isomeric chlorodihydroxybiphenyls for microbial degradation studies of PCBs

Abstract

Monochloro DHBs 1a–d and 2a–c have been regioselectively synthesised in good overall yields by a combination of directed ortho metalation and Suzuki–Miyaura cross-coupling.

Article information

Article type
Paper

Chem. Commun., 1999, 2259-2260

Directed ortho-metalation and Suzuki–Miyaura cross-coupling connections: regiospecific synthesis of all isomeric chlorodihydroxybiphenyls for microbial degradation studies of PCBs

S. Nerdinger, R. Marchhart, P. Riebel, C. Kendall, M. R. Johnson, C.-F. Yin, V. Snieckus and L. D. Eltis, Chem. Commun., 1999, 2259 DOI: 10.1039/A907279I

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