Synthesis and spin-trapping behaviour of glycosylated nitrones

Abstract

In the course of our investigation dealing with the vectorisation and cell targeting of biocompatible spin traps, the synthesis and spin trapping behaviour of two glycosylated nitrones, LAMPBN (N-[4-(lactobionamidomethylene)benzylidene]-N-tert-butylamine N-oxide) and LAMPPN (diethyl [1-methyl-1-[4-(lactobionamidomethylene)benzylidene]azinoylethyl]phosphonate), have been studied and their interactions with yeast bearing specific membrane lectins have been successfully assessed.