New Insights on the Reaction of Alkyl 3-Oxo-4-(triphenylphosphoranylidene)butanoate and Aldehydes under Concentrated Condensation Conditions. One-pot Synthesis of Highly Functionalised 6-Oxocyclohex-4-ene-1,3-dicarboxylates
Abstract
A general method for the synthesis of substituted cyclohexenones 5 from the condensation of acetoacetate phosphonium ylide 1 and saturated and unsaturated aldehydes 2, without activation, is described.