Stereoselective Synthesis of Enantiopure Amino Compounds, via Mitsunobu Azidation of (2S,RS)-1-(p-Tolylsulfinyl)butan-2-ol
Abstract
Azidation of (2S,RS)-1–(p-tolysulfinyl)butan-2-ol under Mitsunobu conditions is the key step for a highly stereoselective preparation of enantiomerically pure amino compounds via chiral sulfoxide chemistry.