Efficient and Catalytic Conversion of Epoxides to 1,3-Dioxolanes with TiO(TFA)2 or TiCl3(OTf)
Abstract
TiO(TFA)2 or TiCl3(OTf) catalyses the efficient reaction of epoxides with acetone to give the corresponding 1,3-dioxolanes in excellent yields. The reaction of chiral styrene oxide was found to be highly stereospecific.