Fractionation of a hexane extract prepared from the plant Schoepfiacalifornica was carried out by bioassay guided fractionation, affording five inhibitors of DNA polymerase β; four of these were shown to be anacardic acid and structurally related derivatives, while the fifth was oleic acid.
J. Chen, Y. Zhang, L. Wang, S. J. Sucheck, A. M. Snow and S. M. Hecht, Chem. Commun., 1998, 2769 DOI: 10.1039/A807053I
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