First total synthesis of (+)-3-deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) from a non-carbohydrate source
Abstract
Enantiopure cis-1,2-dihydrocatechol 2, a product obtained by microbial oxidation of chlorobenzene, has been converted into KDN 1 via a ten step reaction sequence.