Design, synthesis and cleaving activity of an abiotic nuclease based on a manganese(III) porphyrin complex bearing two acridine moieties
Abstract
The synthesis of meso-5,15-bis(m-aminophenyl)porphyrin bearing two acridine derivatives and of its manganese(III) complex was achieved; in the presence of oxygen atom donors, the metalloporphyrin was shown to cleave double-stranded DNA.