A chiral stationary phase HPLC column has been used both to separate the enantiomers of a γ-lactol and also to observe the rate of enantiomerization of the individual enantiomers; the rate of enantiomerization differed for both enantiomers in the presence of the chiral stationary phase.
K. Rossen, J. Sager and Y. Sun, Chem. Commun., 1998, 115 DOI: 10.1039/A706959F
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