Jump to main content
Jump to site search

Issue 1, 1998
Previous Article Next Article

Attachment of human keratinocytes to plasma co-polymers of acrylic acid/octa-1,7-diene and allyl amine/octa-1,7-diene

Abstract

Plasma co-polymers (PCPs) of acrylic acid/octa-1,7-diene and allyl amine/octa-1,7-diene have been prepared and characterised using X-ray photoelectron spectroscopy (XPS). The use of a hydrocarbon diluent in the monomer feed allowed the deposition of films with controlled concentrations of carboxylic acid and nitrogen-containing functional groups. Human keratinocytes were cultured on these PCP surfaces, tissue culture poly(styrene) (TCPS) and collagen I. The level of keratinocyte attachment over 24 h was measured. PCP surfaces containing low concentrations of carboxylic acid groups (2.3%) were found to promote keratinocyte attachment. The performance of these PCPs was similar to collagen I, a well established substratum for attachment. Nitrogen-containing PCP surfaces were found to promote attachment at higher functional group concentrations, although the attachment did not attain the level achieved on the acid functionalised PCP surfaces.

Back to tab navigation

Article information


J. Mater. Chem., 1998,8, 37-42
Article type
Paper

Attachment of human keratinocytes to plasma co-polymers of acrylic acid/octa-1,7-diene and allyl amine/octa-1,7-diene

R. M. France, R. D. Short, R. A. Dawson and S. Macneil, J. Mater. Chem., 1998, 8, 37
DOI: 10.1039/A705098D

Search articles by author

Spotlight

Advertisements