Eclipsed conformations for carbon–oxygen bonds in methoxy derivatives of inositols, sugars and similar compounds

Abstract

Eclipsing of exocyclic carbon–oxygen bonds in methyl ether derivatives of inositols and carbohydrates is reported and discussed. Structural fragments stereotypical for eclipsing are recognised, namely an axial or equatorial alkoxy group on a six-membered ring with equatorial substituents on either side. The X-ray crystal structure of hexa-O-methyl-epi-inositol is reported. Some analogous compounds which also have eclipsed bonds are reported.