Synthesis of pyrido[2,3-c]acridines
Abstract
The synthesis of a range of pyrido[2,3-c]acridines 10, 11, 18 and 20, via imine formation from pyrido-fused cyclohexanones 6, 14 and 16 and anthranilonitrile or anthranilic acid esters, followed by base-catalysed cyclisation and aromatisation, is described.