Issue 3, 1997

Facilitation of displacements at the 6-position of purines by the use of 1,4-diazabicyclo[2.2.2]octane as leaving group

Abstract

Reactions of 6-chloropurines with 1,4-diazabicyclo[2.2.2]octane (DABCO) give the corresponding ‘DABCO-purines’ 1a–d, which undergo facile displacement reactions with alkoxides in dimethyl sulfoxide to afford 6-oxy-substituted purines.

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Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1997, 185-186

Facilitation of displacements at the 6-position of purines by the use of 1,4-diazabicyclo[2.2.2]octane as leaving group

N. K. Lembicz, S. Grant, W. Clegg, R. J. Griffin, S. L. Heath and B. T. Golding, J. Chem. Soc., Perkin Trans. 1, 1997, 185 DOI: 10.1039/A608207F

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