Issue 9, 1997
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Retinoids and related compounds. Part 19.1 Syntheses of 9E- and 9Z-locked retinoic acid analogues and their transcriptional activities as ligands for retinoic acid receptors and retinoid X receptors

Yuko Katsuta,   Yukiko Aoyama,   Hisa Osone,   Akimori Wada  and  Masayoshi Ito  

Abstract

Novel retinoic acid (RA) analogues, 9E-locked-RA 3 and 9Z-locked RA 4, have been synthesized in order to prohibit geometrical isomerization at the C(9)–C(10) double bond when these ligands interact with the retinoic acid receptor (RAR) and retinoid X receptor (RXR). Transcriptional activities of these analogues for RAR and RXR are also described.

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Article information

DOI
https://doi.org/10.1039/A606719K
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1997, 1405-1410

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Retinoids and related compounds. Part 19.1 Syntheses of 9E- and 9Z-locked retinoic acid analogues and their transcriptional activities as ligands for retinoic acid receptors and retinoid X receptors

Y. Katsuta, Y. Aoyama, H. Osone, A. Wada and M. Ito, J. Chem. Soc., Perkin Trans. 1, 1997, 1405 DOI: 10.1039/A606719K

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