The X-ray crystal structure, conformation and preparation of anti-3,3,6,6-tetramethylthiepane-4,5-diol: stereochemistry of reduction of a heterocyclic α-hydroxy ketone
Abstract
The X-ray crystal structure and conformation of the anti title diol is described together with stereoselective syntheses of syn- and anti-diols from a readily available acyloin. Some control of the stereoselective reduction of α-hydroxy ketones by chelating and non-chelating reducing agents is possible.