Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 22nd May 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 16, 1997
Previous Article Next Article

Synthesis of L-selenocystine,L-[77Se]selenocystine andL-tellurocystine

Abstract

Synthetic routes for the synthesis of stable isotope labelled amino acids which contain either a selenium or a tellurium atom have been explored. L-Selenocystine, L-[77Se]selenocystine and L-tellurocystine have been constructed in four steps from commercially available methyl (2S)-2-[(tert-butoxycarbonyl)amino]-3- hydroxypropionate. The sequence of reactions has been successfully scaled up giving significant quantities of the chalcogen based amino acids in fair to good overall yield.

Back to tab navigation

Article type: Paper
DOI: 10.1039/A600180G
J. Chem. Soc., Perkin Trans. 1, 1997, 2443-2448

  •   Request permissions

    Synthesis of L-selenocystine, L-[77Se]selenocystine and L-tellurocystine

    E. M. Stocking, J. N. Schwarz, H. Senn, M. Salzmann and L. A. Silks, J. Chem. Soc., Perkin Trans. 1, 1997, 2443
    DOI: 10.1039/A600180G

Search articles by author

Spotlight

Advertisements