Issue 6, 1997

Studies on Side Chain Interactions during the Isopenicillin N Synthase Catalysed Biosynthesis of Penicillins

Abstract

The role of the L-δ-(α-aminoadipoyl)–Lcys teinyl amide bond in isopenicillin N synthase catalysis is probed by the synthesis of two analogues of its tripeptide substrate L-δ-α-aminoadipoyl-L-cysteinyl- D-valine.

Article information

Article type
Paper

J. Chem. Res. (S), 1997, 200-201

Studies on Side Chain Interactions during the Isopenicillin N Synthase Catalysed Biosynthesis of Penicillins

F. Cavelier, A. T. Russell, C. J. Schofield and J. E. Baldwin, J. Chem. Res. (S), 1997, 200 DOI: 10.1039/A700662D

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