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Issue 14, 1997
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The photochemistry of lomefloxacin. An aromatic carbene as the key intermediate in photodecomposition

Abstract

Irradiation of the 6,8-difluoroquinolone antibiotic lomefloxacin causes selective heterolytic defluorination from position 8 and leads to products rationalized as arising from the cation either via nucleophile addition or intramolecular carbene C–H insertion and hydrogen transfer.

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Article information


Chem. Commun., 1997, 1329-1330
Article type
Paper

The photochemistry of lomefloxacin. An aromatic carbene as the key intermediate in photodecomposition

E. Fasani, M. Mella, D. Caccia, S. Tassi, M. Fagnoni and A. Albini, Chem. Commun., 1997, 1329
DOI: 10.1039/A703226I

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