Issue 10, 1997

Tandem oxa-Michael addition–SN2′ substitution of 4-chlorobut-2-yn-1-ol with nitroalkenes: a total allylic 1,3-strain-controlled diastereoselective synthesis of 3-vinylidenetetrahydrofurans

Abstract

Bu t OK-promoted reaction of 4-chlorobut-2-yn-1-ol 1 with nitroalkenes 2 affords 3-vinylidenetetrahydrofurans 3 in good yields with total diastereoselectivity.

Article information

Article type
Paper

Chem. Commun., 1997, 971-972

Tandem oxa-Michael addition–SN2′ substitution of 4-chlorobut-2-yn-1-ol with nitroalkenes: a total allylic 1,3-strain-controlled diastereoselective synthesis of 3-vinylidenetetrahydrofurans

J. Dulcère and E. Dumez, Chem. Commun., 1997, 971 DOI: 10.1039/A701160A

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