Inclusion effects of cyclodextrins on the catalytic activity of 3-endo-dimethylaminomethyl-1,7,7-trimethylnorbornan-2-endof-amine for the decarboxylation of oxalacetate

Abstract

The inclusion effects of cyclodextrins (CD) on the catalytic activity of 3-endo-dimethylaminomethyl-1,7,7-trimethylnorbornan-2-endo-amine (DTN) for the decarboxylation of oxalacetate have been studied. It was found that β-CD, consisting of seven glucose units, showed a marked enhancement of the catalytic activity of DTN by the inclusion, whereas α-CD showed neither inclusion nor enhancement, and γ-CD showed the inclusion phenomenon, but only with small enhancement. These observations are discussed in terms of the regulation of the DTN conformation by the inclusion.