Acid-catalysed rearrangement of caryophyllene oxide
Abstract
One of the major products 2 from the reaction of caryophyllene oxide in sulfuric acid is shown to arise from rearrangement of the exocyclic double bond and 1,2-epoxide of the starting material to an endocyclic double bond and 1,4-epoxide system. A hydrated 1,5-epoxide was isolated as a minor component of the reaction.