Issue 15, 1996
From the journal:

Chemical Communications

Two antitumour ruthenium(III) complexes showing selectivity in their binding towards poly(dG)·poly(dC) and poly(dA)·poly(dT)

Markus Hartmann,   Thorsten J. Einhäuser  and  Bernhard K. Keppler  

Abstract

The antitumour-active complexes trans-Him[RuIIICl4(im)2](Him = imidazole) and trans-Hind[RuIIICl4(ind)2](Hind = indazole) bind at a higher binding rate to poly(dG)·poly(dC), compared to poly(dA)·poly(dT); the covalent binding to the nucleobases requires a preceding aquation of the compounds, similar to cisplatin.

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Article information

DOI
https://doi.org/10.1039/CC9960001741
Article type
Paper

Chem. Commun., 1996, 1741-1742

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Two antitumour ruthenium(III) complexes showing selectivity in their binding towards poly(dG)·poly(dC) and poly(dA)·poly(dT)

M. Hartmann, T. J. Einhäuser and B. K. Keppler, Chem. Commun., 1996, 1741 DOI: 10.1039/CC9960001741

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