Non-phenolic oxidative coupling of phenol ether derivatives using phenyliodine(III) bis(trifluoroacetate)

Abstract

Phenol ether derivatives (non-phenolic derivatives), 1,3-diarylpropanes 1a–e, N-benzyl-N-phenethylamines 2a–c and N,N-dibenzylamines 3a–e react with a hypervalent iodine reagent, phenyliodine(III) bis(trifluoroacetate)(PIFA), containing BF₃·Et₂O in CH₂Cl₂ to give the biaryl coupling products 4a–e, 5a–c and 6a–e in good yields.