Issue 1, 1996

Catalysis of DNA cleavage by lanthanide complexes with nucleophilic or intercalating ligands and their kinetic characterization

Abstract

The catalysis of plasmid ds-DNA cleavage by lanthanoid cations and their complexes is characterized by saturation kinetics; addition of polyamines or cryptand does not hinder catalysis, which can be enhanced to a total factor of 107 by alcoholic co-substrates such as glycerol, or by intercalating ligands.

Article information

Article type
Paper

Chem. Commun., 1996, 105-107

Catalysis of DNA cleavage by lanthanide complexes with nucleophilic or intercalating ligands and their kinetic characterization

J. Rammo, R. Hettich, A. Roigk and H. Schneider, Chem. Commun., 1996, 105 DOI: 10.1039/CC9960000105

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