Various 3-substituted imidazole 1-oxides have been prepared by reaction of a 1,2-dicarbonyl compound mono- or di-imine with an oxime. The structure of the oxime determines the imidazole C-2 substituent whilst the structure of the mono- or di-imine determines the substitution patterns at N-3, C-4 and C-5.
J. Alcázar, M. Begtrup and A. de la Hoz, J. Chem. Soc., Perkin Trans. 1, 1995, 2467 DOI: 10.1039/P19950002467
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