Alkyl- and aryl-lithiums reacted with noracronycine and 1-hydroxy-3-methoxy-10-methylacridone in a one-step addition–dehydration transformation to provide the corresponding 7- and 9-substituted derivatives having a quinone methide function and, therefore, potential alkylating antitumour properties.
C. Jolivet, C. Rivalle and E. Bisagni, J. Chem. Soc., Perkin Trans. 1, 1995, 511 DOI: 10.1039/P19950000511
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