A novel highly diastereoselective synthesis of chiral dihydrothiophenes from mesoionic compounds
Abstract
Thioisomünchnones undergo 1,3-dipolar cycloaddition with chiral nitroalkenes to afford stereoselectively 4,5-dihydrothiophenes by means of an unprecedented fragmentation of cycloadducts; the structures of these products have been established by single crystal X-ray structure analyses.