Issue 17, 1995

Catalytic asymmetric synthesis of α-methylene-β-hydroxy-ketones

Abstract

Condensation of an α,β-unsaturated ketone, an aldehyde and trimethylsilyl phenyl sulfide or selenide, catalysed by a chiral (acyioxy)borane, and subsequent oxidative elimination gives the title adducts in high enantiomeric excess.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1995, 1755-1756

Catalytic asymmetric synthesis of α-methylene-β-hydroxy-ketones

A. G. M. Barrett and A. Kamimura, J. Chem. Soc., Chem. Commun., 1995, 1755 DOI: 10.1039/C39950001755

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