Dithymidylyl-3′,5′-phosphorofluoridates: new synthesis and stability under solvolytic conditions
Abstract
Dithymidylyl-3′,5′-phosphorofluoridates, prepared by nucleophilic substitution of methylselenyl by fluoride ion, are relatively unstable under solvolytic conditions and undergo rapid base-catalysed hydrolysis/methanolysis.