Diastereoselective reductions of β-substituted-γ-keto sulfoximines and a novel palladium(0)-catalysed allylic sulfoximine to allylic sulfinamide rearrangement
Abstract
The reduction of β-substituted-γ-keto N-tosyl Sulfoximines is highly diastereoselective and the allylic sulfoximines products undergo a facile rearrangement to allylic sulfinamides in the presence of a palladium(0) catalyst.