Tandem Wittig reaction and Cope rearrangement of 2-allyl, 2-dihydroindol-3-ones to 3-indole acetates
Abstract
Treatment of 2-allyl-1,2-dihydroindol-3-ones 1 with phosphonium ylides 2 in refluxing toluene gives 3-indole acetates 4 in good yields by tandem Wittig reaction and aromatization induced Cope rearrangement.