Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 12, 1994
Previous Article Next Article

Semiempirical study of the solvent effect on the Menshutkin reaction

Abstract

The solvent effect on the Menshutkin SN2 reaction of CH3X (X = Cl, Br, I) has been studied using multicavity self-consistent reaction field (MCa SCRF). Two dielectric media, corresponding to hexane and water, have been modelled. The linear and nonlinear structures of the reaction complexes have been used to model the reaction path. The reaction field due to the solvent stabilizes significantly both the transition state and the local minimum of the product of the reaction. The structure of the complexes corresponding to other minima in the reaction path is also discussed. Our results indicate that the reactions of ammonia with methyl chloride, methyl bromide and methyl iodide are exothermic (except methyl iodide in hexane) even in the gas phase, due to the formation of different products (complex between the electroneutral HX and CH3NH2). In hexane, the ion pair CH3NH3+X is formed, whereas in water the reaction results in free ions. A full scheme of the reaction in different media is presented.

Back to tab navigation

Article information


J. Chem. Soc., Perkin Trans. 2, 1994, 2445-2452
Article type
Paper

Semiempirical study of the solvent effect on the Menshutkin reaction

U. Maran, T. A. Pakkanen and M. Karelson, J. Chem. Soc., Perkin Trans. 2, 1994, 2445
DOI: 10.1039/P29940002445

Search articles by author

Spotlight

Advertisements