Conformation of N-cyclopropylcarbonylureas. Solvent polarity dependent chemical shifts
Abstract
The relation between solvent polarity and the chemical shifts of two diastereoisomeric N-cyclopropylcarbonylureas 1 and 2 was examined to elucidate their conformations in solution. In non-polar solvents, where intramolecular hydrogen bonding was playing an important role, their conformations were estimated to be similar to that of 1 in its crystalline state.