Conjugate addition of lithiated 2-heteroaryl-1, 3-dithianes to furan-2(5H)-one has been successfully achieved. This reaction proceeds with higher yields than the addition of the 2-aryl derivatives, although it fails if the heteroaryl ring has strong deactivating substituents.
M. Medarde, A. C. Ramos, R. P. de Clairac, E. Caballero and A. S. Feliciano, J. Chem. Soc., Perkin Trans. 1, 1994, 45 DOI: 10.1039/P19940000045
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