5-Substituted uracil nucleosides useful for the attachment of linker arms to nucleic acids are prepared from arabinoaminooxazoline and dimethyl α-bromomethylfumarate in a short reaction sequence without using any protecting groups, and incorporated into oligodeoxyribonucleotides.
H. Sawai, A. Nakamura, S. Sekiguchi, K. Yumoto, M. Endoh and H. Ozaki, J. Chem. Soc., Chem. Commun., 1994, 1997 DOI: 10.1039/C39940001997
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