α-Alkylation of amines via a 1,5-hydrogen shift
Abstract
Radicals derived from N-(2-iodobenzyl)‘protected’ amines undergo a 1,5-hydrogen shift to give more stable α-amino radicals, which can be subsequently trapped by electron deficient alkenes.
Radicals derived from N-(2-iodobenzyl)‘protected’ amines undergo a 1,5-hydrogen shift to give more stable α-amino radicals, which can be subsequently trapped by electron deficient alkenes.
K. Undheim and L. Williams, J. Chem. Soc., Chem. Commun., 1994, 883 DOI: 10.1039/C39940000883
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