Radical cyclisation of bromomethyldimethylsilyl propynyl ethers; serial radical cyclisations leading to a hydrindene framework from an acyclic substrate, stereoselectively
Abstract
4-Bromomethyldimethylsiloxy-2,8,8-trimethyldec-1-en-5,9-diyne 11 is prepared and its radical cyclisation leads to a stereoselective synthesis of a hydrindene framework 13via three consecutive 5-exo-dig, 5-exo-trig and 6-exo-dig radical processes.