SCHEDULED MAINTENANCE
3-Methyleneindoline derivatives were synthesized by intramolecular Heck reaction of N-allyl-2-iodoaniline derivatives in the presence of Ag2Co3. This method was successfully applied to the synthesis of the CC-1065/duocarmycin pharmacophore.
T. Sakamoto, Y. Kondo, M. Uchiyama and H. Yamanaka, J. Chem. Soc., Perkin Trans. 1, 1993, 1941 DOI: 10.1039/P19930001941
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