Substituted 1-(21-aminovinyl)pyrroles and pyrrolo[1,2-a]pyrazines from the reaction of a pyrazolium methanide 1,3-dipole with dialkyl acetylenedicarboxylates: a 1,2-carbon to nitrogen rearrangement in the pyrazole system
Abstract
Treatment of 1-ethoxycarbonylmethyl-2,3,4,5-tetraaryipyrazolium salts with base in the presence of dialkyl acetylenedicarboxylates provides a new route to substituted 1-(21-aminovinyl)pyrroles and pyrrolo [1,2-a] pyrazines.