Reaction of cis-vicinal dimethanesulfonates with Te2–: a method for converting cis-vicinal diols into olefins and its use in the preparation of 2′,3′-didehydro-2′,3′-dideoxynucleosides
Abstract
cis-Vicinal dimethanesulfonates, prepared from the corresponding diols, are converted into olefins by treatment with alkali metal tellurides or selenides (M2Te or M2Se); the reaction has been used to make derivatives of 2′,3′-didehydro-2′,3′-dideoxynucleosides.