Issue 10, 1993

Efficient photochemical transformation of spiro[4.n]-2,5-diones to γ-alkylidene γ-butyrolactones: its relevance to photostability of Fredericamycin A

Abstract

Irradiation of a variety of model spirodiones related to the antitumour antibiotic Fredericamycin A in various solvents at 300 nm furnishes quantitative yields of γ-alkylidene γ-butyrolactones; its relevance to the typical shape alteration, photostability and consequent biological response of Fredericamycin is discussed.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1993, 870-871

Efficient photochemical transformation of spiro[4.n]-2,5-diones to γ-alkylidene γ-butyrolactones: its relevance to photostability of Fredericamycin A

B. Pandey, R. S. Reddy and P. Kumar, J. Chem. Soc., Chem. Commun., 1993, 870 DOI: 10.1039/C39930000870

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